Hallo, Good Evening, this session will bring a discussion concerning ayushveda ayurveda herbal treatment center hoshiarpur hoshiarpur punjab Autoimmune Bullous Skin Disease Managed with Ayurvedic Treatment: A Case Report see more
Anc Sci Life. 2017 Apr-Jun; 36(4): 229–233.
Abstract
Autoimmune bullous diseases are a group of rare, acquired disorders characterized via overlapping features, opposition to treatment, also future fatality. They want swift also proper management to avoid disastrous complications. Ayurveda is start to provide better release in some autoimmune disorders. Herein, we inform of a 40-year-old male of autoimmune bullous colouring illness (Visphoṭaka) who failed to respond to allopathic medicines also was subsequently treated accompanied by Ayurvedic medicines also achieved complete remission.
Keywords: Autoimmune bullous diseases, Ayurvedic management, Visphoṭaka
Introduction
Auto-immune bullous diseases that include pemphigus vulgaris, paraneoplastic pemphigus, bullous pemphigoid, cicatricial pemphigoid, dermatitis herpetiformis etc., can exist extremely debilitating also fatal. They want in good time also proper medical care to avoid further morbidity or mortality.[1] To control these diseases, mainly physicians use corticosteroids also immunosuppressive drugs as adjuvants.[2] In Ayurveda different herbal also herbo-mineral preparations are described which are start to exist successful in autoimmune diseases. Among them, herbo-mineral preparations such as Ārogyavardhinī Rasa[3] also Gandhaka Rasāyana[4] are widely prescribed via Ayurvedic physicians also are reported to provide promising results in a wide range of colouring disorders. Some Ayurvedic herbs are and start successful in management of colouring diseases internally also externally. Herein we inform of in this event study, a case diagnosed accompanied by Autoimmune bullous condition (bullous pemphigoid) also was favourably treated accompanied by Ayurvedic management.
Case Report
A 40 year old, non-diabetic male patient, employed in Brass industry was presented accompanied by two months history of constant extensive also critical stomatitis accompanied by recurrent oral ulcers leading to difficulty in oral food intake even in liquid form. Recurrent flaccid, fluid filled bullae all on top of body were and present, which turned to crusting erosions at the end of getting ruptured throughout way of healing. He was having redness, critical pain, burning, non foul smelling, serous oozing from lesions also disturbed sleep. He was diagnosed as a event of lichen planus two months back also after on top of was primarily diagnosed via another dermatologist as a event of bullous colouring condition (?bullous pemphigoid) [Table 1]. The clinical signs also symptoms similar to erythema, urticaria nearby the bullae, tense bullae also balanced hemorrhagic blisters were suggestive of bullous pemphigoid.[5] Due to the poor fair order of the patient, biopsy or tzanck smear investigation was not possible appropriate to solid diagnosis.
Table 1
Treatment provided previously via two dermatologists
Due to insignificant release of the therapy, the case was referred appropriate to Ayurvedic medication [Table 1]. The case was clinically diagnosed as Visphoṭaka (bullous colouring disorder) also hospitalized in indoor case department also was put on top of under described Ayurvedic management [Table 2]. Blisters all on top of the body united accompanied by burning sensation, fever also thirstiness are the symptoms of Visphoṭaka described in Ayurvedic classics.[6,7] In pathogenesis of Visphoṭaka, tridoṣas (vāta, pitta also kapha) are involved accompanied by predominance of pitta also kapha.[8] Treatment prescribed via dermatologist was withheld. The case was prescribed oral administration of Arogyavardhini Rasa also Gandhaka Rasāyana, single gm every also combination of powders of Guḍūcī[9] (Tinospora cordifolia Willd.), Khādira[10] (Acacia Catechu Willd.) also Vasā[11] (Adhatoda vasica Nees.), three gram each, twice daily; Local application of concentrated Pañcavalkala Kvātha[12] [decoction of the barks of five herbs, namely Ficus benghalensis Linn. (Vaṭa), Ficus glomerata Roxb. (Udumbara), Ficus religiosa Linn. (Aśvattha), Thespesia populnea Soland. ex Correa. (Pāriśa) also Ficus lecor Buch. Ham. (Plakṣa)] was prescribed throughout the medical care period. He was evaluated appropriate to programme haematological, urine also biochemical investigations on top of admission also before discharge. Pain also burning sensation were start decreased at the end of local application. On sixth twenty-four hours of hospitalization, generalized itching was observed but the formation of modern bullae was start decreased. Upon improvement of status of agni, on top of 11th day, Pañcatikta Ghṛta[13] [ghee based preparation of 5 bitter herbs viz. Azadirachta indica Linn. (Nimba), Luffa acutangula (L.) Roxb. (Paṭola), Solanum surattense Burm. F. (Kaṇṭakārī), Tinospora cordifolia (Willd.) Miers. (Guḍūcī) also Adhatoda vasica Nees.(Vasā)] 30 ml orally accompanied by warm express milk from on single occasion in the before noon empty stomach was extra to over described treatment. Dose of Pañcatikta Ghṛta was increased to 40 ml per twenty-four hours on top of 13th twenty-four hours also 50 ml per twenty-four hours from 21st twenty-four hours at the end of assessment of status of agni also palatability which was continued till the twenty-four hours of discharge. Frequency of modern formation of bullae, oozing was significantly reduced on top of 13th day, accompanied by clear medicinal of older lesions also complete cessation of formation of modern bullae from 16th twenty-four hours onwards. There was clear improvement in trap ulcers, difficulty in food intake also sleep on top of 13th day. 90% of the lesions healed inside 20 days. Generalized itching reduced via 22nd twenty-four hours of treatment. There was reduction in raised mass WBC count, ESR also Eosinophils [Table 3]. Biochemical markers were inside normal limits before discharge [Table 4]. On the twenty-four hours of discharge (30th day), all colouring lesions were healed also similar ongoing medical care was prescribed on top of the twenty-four hours of discharge. This showed great results [Figure 1]. There was certainly not fever also a bit of medical or surgical emergency throughout hospital stay. Pañcatikta Ghṛta (20 ml accompanied by express milk from one time in morning) was prescribed appropriate to 6 months also Ārogyavardhinī rasa, Gandhaka rasāyana also combination of Guḍūcī, Khādira also Vasā were continued appropriate to single year in the follow-up period. During follow up period, certainly not recurrence was observed. Generalized itching, clear on top of forearms also hands was noted throughout follow up, which was probably expected to chemical exposure also this subsided inside two to three days accompanied by local application of Pañcavalkala Kvātha. No adverse medication reaction was noticed throughout medical care also follow up period.
Table 2
Ayurvedic treatment
Table 3
Comparative haematological parameters of the patient
Table 4
Comparative bio-chemical parameters of the patient
(a, c, e, g) Prior to Ayurvedic management showing active lesions on top of abdomen, hand, thigh also leg. (b, d, f, h) 30 days at the end of showing complete remission
Discussion
Conventional (allopathic) anti-inflammatory drugs are the mainstay of medical care appropriate to different auto-immune disorders. Owing to the border belongings also the high cost of conventionally used anti-inflammatory drugs; patients are increasingly using matching also substitute remedy (CAM) modalities of treatment.[14] Here the case had critical spread of the condition also did not enhance accompanied by the conservative medical care modalities. Because of the secondarily infected colouring erosions, life-threatening sepsis had developed. Therefore, it was definite to treat him accompanied by Ayurvedic management. On re-examination of Ayurvedic classics, various medicines are start most recommended appropriate to different auto-immune colouring disorders. Safety also efficacy of Ārogyavardhinī rasa own been proven via study scholars.[15] Picrorhiza kurroa, a major component of Ārogyavardhinī rasa, has choleretic effects.[16] Along accompanied by this we started the combination of three potent herbs appropriate to getting swift belongings also start great results in all symptoms. As Ayurvedic single formulation contains various herbs also minerals, proper mode of action of the formulation is difficult to describe. Various researches own proven the pharmacological actions of the medicines used in this event [Table 5]. Among the medicines, Khādira, Vasā, Pañcatikta ghṛta also Pañcavalkala Kvātha may own caused anti incendiary effect, while Guḍūcī also Pañcatikta ghṛta the immuno-modulatory effect. Wound medicinal properties of topical formulation helped in medicinal of wound created via blisters. Anti microbial, Anti fungal, analgesic also hepato-protective actions avoid united symptoms of the disease.
Table 5
Proven pharmacological actions of the prescribed formulations
Conclusion
The presented combination also management via Ayurvedic medicament is start to exist a great substitute treatment in autoimmune bullous disorder. Long-term prospective studies are obligatory to substantiate the data.
Declaration of case consent
The authors show that they own obtained all appropriate case consent forms. In the form, the case has given his consent appropriate to his images also additional clinical information to exist reported in the journal. The case get that nickname also initials will not exist published also expected efforts will exist made to conceal identity, but anonymity cannot exist guaranteed.
Financial support also sponsorship
Nil.
Conflicts of interest
There are certainly not conflicts of interest.
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